• Nemesis (mythology), the Greek goddess of retribution

• Archenemy, the principal enemy of a character in a work of fiction

Literature

• Nemesis (play), by Alfred Nobel

• "Nemesis" (short story), by Arthur C. Clarke

• Nemesis (Agatha Christie novel), a 1971 detective novel

• Nemesis (Isaac Asimov novel), a 1989 science fiction novel

• Nemesis (Nesbo novel), a 2002 crime novel in the Harry Hole series

• Nemesis (Angel novel), a 2004 novel based on the Angel series

• Nemesis (Philip Roth novel), a 2010 dramatic novel

• Nemesis, a 2004 fantasy series by Wolfgang Hohlbein

• Nemesis, a 1989 fantasy novel in the Indigo series by Louise Cooper

• Nemesis, a 1998 thriller novel by Bill Napier

• Nemesis: The Last Days of the American Republic by Chalmers Johnson

• Hitler 1936–1945: Nemesis, by Ian Kershaw

• Nemesis: The Battle for Japan, 1944-45, by Max Hastings

• Nemesis: The Death Star, by Richard A. Muller

• The Nemesis Affair: A Story of the Death of Dinosaurs and the Ways of Science by David M. Raup

Gaming

• Nemesis (Magic: The Gathering)

• Nemesis (role-playing game)

• Nemesis (handheld game)

• Nemesis (arcade game)

• Resident Evil 3: Nemesis, a 1999 video game

• * Nemesis (Resident Evil), a character in the game

• Zork Nemesis, a computer game in the Zork series

• Nemesis, a monster in the video game Dark Sector

Film and television

• Nemesis (film), a 1992 science fiction film

• "Nemesis" (Voyager episode)

• "Nemesis" (Stargate SG-1)

• Star Trek Nemesis, a 2002 film

Music

Performers

• Nemesis (band), a South Korean rock band

• Nemesis (Sri Lankan band), a heavy metal band

• Nemesis (pop music duo)

• Nemesis (rap crew)

• Nemesis, a Swedish band featuring Leif Edling

Releases

• Nemesis (album), by Grip Inc.

• "Nemesis," a song by Arch Enemy on the album Doomsday Machine

• "Nemesis," a song by Cradle of Filth on the album Nymphetamine

• "Nemesis," a song by David Gray on the album Draw the Line

• "Nemesis," a song by Aaron Parks on the album Invisible Cinema

• "Nemesis," a song by Shriekback on the album Oil & Gold

• "Nemesis," a song by TheStart on the album Shakedown!

• "Nemesis," a song by VNV Nation on the album Judgement

Military and defense

• , the name of several Royal Navy ships

• USS Nemesis (1869), a U.S. Navy ship

• HEIC Nemesis, a British warship used in the First Opium War

• Operation Nemesis, a 1920s Armenian military operation

• AN/AAQ-24 Nemesis, a directed infrared countermeasure system for aircraft defense

Other uses

• Nemesis (comics), the name of several comics characters

• Nemesis (Transformers), a fictional starship

• Nemesis (drug)

• Nemesis (operating system)

• Nemesis (roller coaster)

• Nemesis (star)

• 128 Nemesis, an asteroid

• Bowler Nemesis, an off-road racing vehicle

• Sharp Nemesis, a racing aircraft

• A classification of emotion in Aristotle's Nicomachean Ethics