Events of 1522

January–June

July 28: Knights of St. John.

• January 9 – Pope Adrian VI (born Adrian Dedens and sometimes referred to as Hadrian) succeeds Pope Leo X as the 218th pope.

• April 27 – Battle of Bicocca: French and Swiss forces under Odet de Lautrec are defeated by the Spanish in their attempt to retake Milan, and are forced to withdraw into Venetian territory.

December 20: Knights of Malta.

July–December

• July 28 – Ottoman Sultan Suleiman I begins his siege of the Knights of St. John in Rhodes.

• September 6 – The Vittoria, one of the surviving ships of Ferdinand Magellan's expedition, returns to Sanlucar de Barrameda in Spain, becoming the first ship to circumnavigate the world.

• December 18 – The Turks finally break into Rhodes, but the Knights continue fierce resistance in the streets.

• December 20 – Suleiman the Magnificent accepts the surrender of the surviving Knights, who are allowed to evacuate. They eventually re-settle on Malta and become known as the Knights of Malta.

3rd Textus Receptus.

Undated

• The first Diet of Nuremberg is held.

• The third edition of the Textus Receptus of the Bible is published.

• The Knight's Revolt erupts in Germany.

• Chinese Ming Dynasty records indicate that the War Ministry official He Ru is the first to acquire the Portuguese breech-loading culverin, while copies of them are made by two Westernized Chinese at Beijing, Yang San (Pedro Yang) and Dai Ming.

• The Habsburg-Valois Wars begin.

• Costa Rica was named by the Spanish Colonizer Gil González Dávila when he found copious quantities of gold in Caribbean beaches.

• Some believe that Australia was sighted by a Portuguese expedition led by Cristóvão de Mendonça. They mapped the continent and named it Jave la Grande, meaning The Greater Java.

Births

• February 2 – Lodovico Ferrari, Italian mathematician (d. 1565)

• March 28 – Albert the Warlike, German prince (d. 1557)

• April 23 – Catherine of Ricci, Italian prioress (d. 1590)

• May 24 – John Jewel, English bishop (d. 1571)

• July 25 – Anna of Lorraine (d. 1568)

• September 11 – Ulissi Aldrovandi, Italian naturalist (d. 1605)

• November 9 – Martin Chemnitz, Lutheran reformer (d. 1586)

• November 18 – Lamoral, Count of Egmont, Flemish general and statesman (d. 1568)

• December 28 – Margaret of Austria, regent of the Netherlands (d. 1568)

• date unknown

• *Rabbi Moses ben Jacob Cordovero [RaMaK]- Jewish kabbalist from Safed, Israel [d. 1570)

• probable

• *Emperor Gelawdewos of Ethiopia (d. 1559)

Deaths

• February 25 – William Lilye, English classical scholar (b. c. 1468)

• April – Queen Eleni of Ethiopia

• June 25 – Franchinus Gaffurius, Italian composer (b. 1451)

• June 30 – Johann Reuchlin, German humanist and Hebrew scholar (b. 1455)

• September – Gavin Douglas, Scottish poet and bishop (b. c. 1474)

• October 30 – Jean Mouton, French composer (b. c. 1459)

• November 14 – Anne of France, Princess and Regent of France (b. 1461)

• date unknown

• *Fiorenzo di Lorenzo, Italian painter (b. 1440)

• *Henry Stafford, 1st Earl of Wiltshire, English nobleman (b. 1479)